Nigerian representatives were matched against tough teams in the round of the 16 stage of the CAF Confederation Cup.
Enyimba FC, Plateau United, Akwa United and MFM FC avoided each other in the draws which took place on Thursday.
Two-time CAF Champions League champions, Enyimba FC will need to navigate past South African outfit Bidvest Wits.
Plateau United were drawn against Algerian powerhouse USM Algiers while Akwa United will face Sudan’s Al Hilal.
Fidelis Ilechukwu’s MFM FC who were humbled 7-2 on aggregate in the CAF Champions League have Djoliba to contend with.
Winners over two legs will advance to the group stage of the second-tier African club competition.